SCHEMBL24826547

SCHEMBL24826547

c1ccc(-c2ccccc2N(c2ccc(-c3cc4ccccc4c4ccccc34)cc2)c2cccc3ccc4c5ccccc5oc4c23)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.37
CYP19A1 P11511 1/20 0.32
ALDH1A1 P00352 3/20 0.32
RAB9A P51151 2/20 0.32
KDM4E B2RXH2 2/20 0.32
MAOB P27338 1/20 0.32
HPGD P15428 2/20 0.32
PRKDC P78527 1/20 0.32
ERBB2 P04626 1/20 0.32
CYP1A2 P05177 1/20 0.32
FYN P06241 1/20 0.32
MAOA P21397 1/20 0.32
ACHE P22303 1/20 0.32
AHR P35869 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24825721 0.95 ALOX5 (0.38) ALOX5CYP19A1ALDH1A1RAB9AKDM4E
SCHEMBL24656865 0.94 ALOX5 (0.36) ALOX5CYP19A1ALDH1A1RAB9AKDM4E
SCHEMBL26061304 0.94 ALOX5 (0.36) ALOX5CYP19A1ALDH1A1KDM4EHPGD
SCHEMBL26020266 0.94 ALOX5 (0.37) ALOX5CYP19A1ALDH1A1HPGDPRKDC
SCHEMBL24826691 0.94 ALOX5 (0.36) ALOX5CYP19A1ALDH1A1RAB9AKDM4E
SCHEMBL26021168 0.93 ALOX5 (0.37) ALOX5CYP19A1ALDH1A1HPGDPRKDC
SCHEMBL24887675 0.93 ALOX5 (0.38) ALOX5CYP19A1ALDH1A1KDM4EPRKDC
SCHEMBL26021181 0.91 ALOX5 (0.37) ALOX5CYP19A1ALDH1A1HPGDPRKDC
SCHEMBL24826559 0.91 ALOX5 (0.36) ALOX5PRKDCERBB2CYP1A2FYN
SCHEMBL24826551 0.91 ALOX5 (0.38) ALOX5ALDH1A1KDM4EHPGDPRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023287228-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2023-01-19 WO disclosed
US-20220416174-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-29 US disclosed