SCHEMBL24827451

SCHEMBL24827451

C=CC(=O)OCCCCOc1ccc(C(=O)Nc2ccc(C#Cc3ccc4cc(OCCCCOC(=O)C=C)ccc4c3)cc2C(F)(F)F)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
RAB9A P51151 1/20 0.40
PLK1 P53350 3/20 0.37
CA9 Q16790 3/20 0.36
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.36
THRB P10828 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
ACAT1 P24752 1/20 0.35
ROCK2 O75116 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20883274 0.94 CYP1A2 (0.42) CYP1A2CYP2D6CYP2C19RAB9APLK1
SCHEMBL20883275 0.94 CYP1A2 (0.42) CYP1A2CYP2D6CYP2C19RAB9APLK1
SCHEMBL24807970 0.89 PLK1 (0.39) CYP1A2CYP2D6CYP2C19RAB9APLK1
SCHEMBL21339804 0.86 THRB (0.40) CYP1A2CYP2D6CYP2C19HPGDTHRB
SCHEMBL25015316 0.84 CYP1A2 (0.40) CYP1A2CYP2D6CYP2C19RAB9APLK1
SCHEMBL15425220 0.83 CYP1A2 (0.42) CYP1A2CYP2D6CYP2C19RAB9APLK1
SCHEMBL20883273 0.82 MAPT (0.45) POLBTHRBLMNAMAPT
SCHEMBL20883272 0.82 NPC1 (0.43) CYP1A2CYP2C19RAB9APLK1THRB
SCHEMBL20883220 0.80 MAPT (0.48) CYP1A2RAB9APLK1THRBLMNA
SCHEMBL21339801 0.80 ACACB (0.40) CYP1A2CYP2D6CYP2C19THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022270563-A1 COMPOUND, COMPOSITION, CURED PRODUCT, OPTICALLY ANISOTROPIC BODY, OPTICAL ELEMENT, AND LIGHT GUIDE ELEMENT 富士フイルム株式会社 2022-12-29 WO disclosed