SCHEMBL2482887

SCHEMBL2482887

Fc1cc(F)cc(-c2cnc3ccccc3n2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 11/20 0.56
RAB9A P51151 9/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
BCHE P06276 2/20 0.56
MAPT P10636 4/20 0.50
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 3/20 0.50
HPGD P15428 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ACHE P22303 1/20 0.50
TLR9 Q9NR96 1/20 0.47
GAA P10253 2/20 0.46
PDGFRB P09619 1/20 0.46
KDR P35968 1/20 0.46
FLT3 P36888 1/20 0.46
CASP1 P29466 1/20 0.46
MAPK10 P53779 1/20 0.46
CASP7 P55210 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18806858 0.86 NPC1 (0.66) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL15112605 0.86 BCHE (0.68) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL1976848 0.83 NPC1 (0.68) NPC1RAB9ASMN1; SMN2BCHEMAPT
Water SCHEMBL27680272 0.81 NPC1 (0.66) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL4954320 0.80 NPC1 (0.81) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL1147294 0.78 MAPK14 (0.55) MAPTKDM4EALDH1A1L3MBTL1TLR9
SCHEMBL87505 0.78 NPC1 (0.71) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL29371290 0.78 NPC1 (0.71) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL18883005 0.78 NPC1 (0.65) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL29966674 0.77 NPC1 (0.63) NPC1RAB9ASMN1; SMN2BCHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1749424-B1 LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2011-10-19 EP disclosed
EP-1749424-A4 LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2009-04-22 EP disclosed
EP-1749424-A1 LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-07 EP disclosed
WO-2005115061-A1 LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2005-12-01 WO disclosed
US-20050191527-A1 Organometallic compound containing quinoxaline structure and light emitting element SANYO ELECTRIC CO., LTD. (JP) 2005-09-01 US disclosed