SCHEMBL1147294

SCHEMBL1147294

Fc1cc(F)cc(-c2nc3ccccc3nc2-c2cc(F)cc(F)c2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 5/20 0.55
MAPK10 P53779 2/20 0.55
KDM4E B2RXH2 5/20 0.45
L3MBTL1 Q9Y468 4/20 0.45
KMT2A Q03164 2/20 0.45
LMNA P02545 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
GAA P10253 1/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.43
ALDH1A1 P00352 2/20 0.42
ATM Q13315 1/20 0.42
TLR9 Q9NR96 1/20 0.42
USP2 O75604 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP2C19 P33261 1/20 0.42
ADORA2A P29274 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28276494 0.83 ADORA2A (0.60) MAPK14MAPK10KDM4EL3MBTL1KMT2A
SCHEMBL17942582 0.79 NPC1 (0.43) MAPK14MAPK10KDM4EL3MBTL1KMT2A
SCHEMBL14842570 0.79 MAPK10 (0.38) MAPK14MAPK10KMT2ALMNAMEN1
SCHEMBL14842599 0.79 ALDH1A1 (0.42) MAPK14MAPK10KDM4EKMT2AGAA
SCHEMBL14842568 0.79 MAPK14 (0.39) MAPK14MAPK10KMT2AMEN1ALDH1A1
SCHEMBL71619 0.79 MAPK14 (0.81) MAPK14MAPK10KDM4EL3MBTL1KMT2A
SCHEMBL29405271 0.79 MAPK14 (0.81) MAPK14MAPK10KDM4EL3MBTL1KMT2A
SCHEMBL2482887 0.78 NPC1 (0.56) MAPK10KDM4EL3MBTL1GAAMAPT
SCHEMBL14842601 0.78 MAPK14 (0.41) MAPK14MAPK10KMT2ALMNAMEN1
SCHEMBL29767839 0.77 MAPK14 (0.78) MAPK14MAPK10KDM4EL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8637167-B2 Light emitting element and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-28 US disclosed
US-8637167-B2 Light emitting element and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-28 US disclosed
US-8637167-B2 Light emitting element and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-28 US disclosed
US-8227600-B2 Organometallic complex, and light-emitting element and light-emitting device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-24 US disclosed
US-8227600-B2 Organometallic complex, and light-emitting element and light-emitting device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-24 US disclosed
US-8227600-B2 Organometallic complex, and light-emitting element and light-emitting device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-24 US disclosed
EP-1749424-B1 LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2011-10-19 EP disclosed
US-20110196152-A1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-08-11 US disclosed
US-20110196152-A1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-08-11 US disclosed
US-20110196152-A1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-08-11 US disclosed
US-7811677-B2 Light emitting element and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-10-12 US disclosed
US-7811677-B2 Light emitting element and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-10-12 US disclosed
US-7811677-B2 Light emitting element and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-10-12 US disclosed
US-20080113216-A1 Organometallic Complex, And Light-Emitting Element And Light-Emitting Device Using The Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-15 US disclosed
US-20080113216-A1 Organometallic Complex, And Light-Emitting Element And Light-Emitting Device Using The Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-15 US disclosed
US-20080113216-A1 Organometallic Complex, And Light-Emitting Element And Light-Emitting Device Using The Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-15 US disclosed
US-20070241667-A1 Light Emitting Element and Light Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-10-18 US disclosed
US-20070241667-A1 Light Emitting Element and Light Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-10-18 US disclosed
US-20070241667-A1 Light Emitting Element and Light Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-10-18 US disclosed
WO-2006062144-A1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING ELEMENT AND LIGHT-EMITTNG DEVICE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110196152-A1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE USING THE SAME C5, CRY1, ORC3 MAPK14 4530/4885MAPK10 4201/4885KDM4E 2114/4885
US-20070241667-A1 Light Emitting Element and Light Emitting Device LAGE3, MT-ND5, NDUFS5 MAPK14 4158/4885MAPK10 4165/4885KDM4E 1959/4885
US-20080113216-A1 Organometallic Complex, And Light-Emitting Element And Light-Emitting Device Using The Same C5, CRY1, ORC3 MAPK14 4530/4885MAPK10 4201/4885KDM4E 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.