Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1051352 | 1.00 | CTRB1 (0.76) | CTRB1CYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL2435512 | 1.00 | CTRB1 (0.76) | CTRB1CYP3A4MAPK1ALDH1A1CYP1A2 | |
| Carbamic Acid SCHEMBL8426387 | 0.96 | CTRB1 (0.70) | CTRB1CYP3A4MAPK1ALDH1A1CYP1A2 | |
| Carbamic Acid SCHEMBL8426357 | 0.96 | CTRB1 (0.70) | CTRB1CYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL3126143 | 0.94 | CTRB1 (0.68) | CTRB1CYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL8612701 | 0.94 | CTRB1 (0.68) | CTRB1CYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL7342331 | 0.93 | CTRB1 (0.67) | CTRB1CYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL4829896 | 0.92 | CTRB1 (0.68) | CTRB1ALDH1A1CYP1A2SMN1; SMN2TACR1 | |
| SCHEMBL7301416 | 0.91 | CTRB1 (0.64) | CTRB1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9484576 | 0.91 | CTRB1 (0.64) | CTRB1CYP3A4CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4633581-A1 | A TOPICAL COMPOSITION | Rock & Herb Pte Ltd (SG) | 2025-10-22 | — | — | EP | claimed |
| WO-2024128980-A1 | A TOPICAL COMPOSITION | ROCK & HERB PTE LTD (SG) | 2024-06-20 | — | — | WO | claimed |
| EP-0815074-B1 | O-CARBAMOYL-(D)-PHENYLALANILOL COMPOUNDS AND PROCESS FOR PREPARING THE SAME | SK CORP (KR) | 2001-10-04 | — | — | EP | claimed |
| EP-0728129-B1 | NOVEL PHENYLALKYLAMINOALCOHOL CARBAMATES AND PROCESS FOR PREPARING THE SAME | YUKONG LTD (KR) | 1999-11-03 | — | — | EP | claimed |
| US-5955499-A | PHARMACEUTICALS USEFUL TO TREAT DISEASES OF THE CENTRAL NERVOUS SYSTEM, I.E. ANTIDEPRESSANTS | YUKONG LIMITED (KR) | 1999-09-21 | — | — | US | claimed |
| EP-0815074-A1 | O-CARBAMOYL-(D)-PHENYLALANILOL COMPOUNDS AND PROCESS FOR PREPARING THE SAME | YUKONG LIMITED (KR) | 1998-01-07 | — | — | EP | claimed |
| EP-0728129-A1 | NOVEL PHENYLALKYLAMINOALCOHOL CARBAMATES AND PROCESS FOR PREPARING THE SAME | YUKONG LIMITED (KR) | 1996-08-28 | — | — | EP | claimed |
| WO-1996024577-A1 | O-CARBAMOYL-(D)-PHENYLALANILOL COMPOUNDS AND PROCESS FOR PREPARING THE SAME | YUKONG LIMITED (KR) | 1996-08-15 | — | — | WO | claimed |
| WO-1996007637-A1 | NOVEL PHENYLALKYLAMINOALCOHOL CARBAMATES AND PROCESS FOR PREPARING THE SAME | YUKONG LIMITED (KR) | 1996-03-14 | — | — | WO | claimed |
| EP-4688731-A1 | PROCESS FOR PREPARING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE | INKE, S.A. (ES) | 2026-02-11 | — | — | EP | disclosed |
| EP-4633581-A1 | A TOPICAL COMPOSITION | Rock & Herb Pte Ltd (SG) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024208791-A1 | PROCESS FOR PREPARING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE | INKE, S.A. (ES) | 2024-10-10 | — | — | WO | disclosed |
| US-20240208992-A1 | MACROCYCLES AS CFTR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-27 | — | — | US | disclosed |
| WO-2024128980-A1 | A TOPICAL COMPOSITION | ROCK & HERB PTE LTD (SG) | 2024-06-20 | — | — | WO | disclosed |
| US-5157143-A | DIASTEREOSELECTIVE PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE SYNTHESIS OF PEPTIDE DERIVATIVES | ZAMBON GROUP S.P.A. (IT) | 1992-10-20 | — | — | US | disclosed |
| EP-0341462-B1 | DIASTEREOSELECTIVE PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE SYNTHESIS OF PEPTIDE DERIVATIVES | ZAMBON GROUP S.p.A. (IT) | 1992-09-09 | — | — | EP | disclosed |
| EP-0439556-A1 | HETEROCYCLIC PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1991-08-07 | — | — | EP | disclosed |
| WO-1990004917-A1 | HETEROCYCLIC PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1990-05-17 | — | — | WO | disclosed |
| EP-0365992-A1 | Heterocyclic peptide renin inhibitors | ABBOTT LABORATORIES (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0341462-A1 | Diastereoselective process for the preparation of intermediates useful for the synthesis of peptide derivatives | ZAMBON GROUP S.p.A. (IT) | 1989-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208992-A1 | MACROCYCLES AS CFTR MODULATORS | CFTR, PKD1, ARRB1 | CTRB1 316/4885CYP3A4 1162/4885MAPK1 2666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.