SCHEMBL2482983

SCHEMBL2482983

COc1ccc(C=Nc2ccc(C#N)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.64
PTGS2 P35354 2/20 0.56
PTGS1 P23219 1/20 0.56
CA12 O43570 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
ALDH1A1 P00352 7/20 0.47
KDM4E B2RXH2 4/20 0.47
GAA P10253 3/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 4/20 0.46
HPGD P15428 2/20 0.46
ACHE P22303 2/20 0.46
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
NPSR1 Q6W5P4 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3181342 1.00 S100B (0.64) S100BPTGS2PTGS1CA12CA2
SCHEMBL295243 1.00 S100B (0.64) S100BPTGS2PTGS1CA12CA2
SCHEMBL2482981 1.00 S100B (0.64) S100BPTGS2PTGS1CA12CA2
SCHEMBL10413111 0.95 S100B (0.59) S100BPTGS2PTGS1CA12CA2
SCHEMBL10413110 0.95 S100B (0.59) S100BPTGS2PTGS1CA12CA2
SCHEMBL4688279 0.94 S100B (0.57) S100BPTGS2PTGS1CA12CA2
SCHEMBL4787112 0.93 S100B (0.56) S100BPTGS2PTGS1CA12CA2
SCHEMBL4787108 0.93 S100B (0.56) S100BPTGS2PTGS1CA12CA2
SCHEMBL10412841 0.86 S100B (0.82) S100BPTGS2PTGS1CA12CA2
SCHEMBL10733285 0.86 S100B (0.82) S100BPTGS2PTGS1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3469576-B1 MULTI-LAYER DISPLAY WITH COLOR AND CONTRAST ENHANCEMENT SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-03 EP disclosed
CN-109478389-B Multi-layer display with color and contrast enhancement 三星电子株式会社 2023-01-10 CN disclosed
CN-109477972-B Multi-layer high transparency display for light field generation 三星电子株式会社 2022-02-22 CN disclosed
US-20220050316-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2022-02-17 US disclosed
CN-110483308-B Method for preparing secondary amine compound by imine hydrogenation reduction 大连理工大学 2021-08-20 CN disclosed
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 US disclosed
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 EP disclosed
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 EP disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 US disclosed
EP-0787419-A1 ELECTROLUMINESCENT DEVICE Koninklijke Philips Electronics N.V. (NL) 1997-08-06 EP disclosed
WO-1997007654-A1 ELECTROLUMINESCENT DEVICE PHILIPS ELECTRONICS N.V. (NL) 1997-02-27 WO disclosed
EP-0747461-A1 Polymer stabilized liquid crystals and flexible devices thereof Sniaricerche S.C.P.A. (IT) 1996-12-11 EP disclosed
WO-1995001410-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S.C.P.A. (IT) 1995-01-12 WO disclosed
US-4101207-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1978-07-18 US disclosed
US-4097776-A Coated electroluminescent phosphors THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1978-06-27 US disclosed
US-4035060-A Electro-optic device DAINIPPON PRINTING CO., LTD (JA) 1977-07-12 US disclosed
US-3991241-A A CARBOXYLATOCHROMIUM(III) COMPLEX TOKYO SHIBAURA ELECTRIC CO., LTD. (JA) 1976-11-09 US disclosed
US-3944330-A Electro-optic device DAINIPPON PRINTING CO., LTD. (JA) 1976-03-16 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed