Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | PYGM | P11217 | 4/20 | 0.46 |
| ▸ | PYGL | P06737 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GGT1 | P19440 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842596 | 0.89 | CTNNB1 (0.49) | CTNNB1KDM4EPOLBALDH1A1AKR1C3 | |
| SCHEMBL28560551 | 0.88 | KDM4E (0.63) | CTNNB1KDM4EPOLBHTTALDH1A1 | |
| SCHEMBL7457156 | 0.88 | CTNNB1 (0.49) | CTNNB1KDM4EPOLBAKR1C3PYGM | |
| SCHEMBL28264707 | 0.86 | KDM4E (0.61) | CTNNB1KDM4EPOLBHTTALDH1A1 | |
| SCHEMBL921873 | 0.85 | AKR1C3 (0.69) | CTNNB1KDM4EPOLBHTTALDH1A1 | |
| SCHEMBL1798 | 0.82 | CTNNB1 (0.71) | CTNNB1KDM4EHTTALDH1A1HPGD | |
| SCHEMBL742799 | 0.82 | CTNNB1 (0.53) | CTNNB1KDM4EPOLBHTTALDH1A1 | |
| SCHEMBL30975119 | 0.82 | CTNNB1 (0.53) | CTNNB1KDM4EPOLBHTTALDH1A1 | |
| SCHEMBL24407810 | 0.81 | CTNNB1 (0.56) | CTNNB1KDM4EPOLBHTTALDH1A1 | |
| SCHEMBL15304483 | 0.81 | AKR1C3 (0.54) | CTNNB1KDM4EPOLBHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003295-A1 | MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |
| EP-2376197-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2011-10-19 | — | — | EP | disclosed |