Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 5/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | IL1B | P01584 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 4/20 | 0.41 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.41 |
| ▸ | SALL4 | Q9UJQ4 | 2/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 8/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25513494 | 0.87 | CRBN (0.65) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL22812461 | 0.85 | CRBN (0.50) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL22046158 | 0.85 | CRBN (0.65) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL24637351 | 0.85 | CRBN (0.50) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL27330493 | 0.82 | CRBN (0.47) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL24920904 | 0.79 | CRBN (0.61) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL24592273 | 0.79 | CRBN (0.61) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL19436868 | 0.79 | CRBN (0.75) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL31727974 | 0.79 | CRBN (0.75) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL29359672 | 0.79 | CRBN (0.75) | CRBNIKZF3IKZF1TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4112614-A1 | GLUTARIMIDE SKELETON-BASED COMPOUNDS AND APPLICATION THEREOF | Shanghaitech University (CN) | 2023-01-04 | — | — | EP | disclosed |