SCHEMBL2483147

SCHEMBL2483147

CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@H](COC(c2ccccc2)(c2ccccc2)c2ccc(OC)cc2)[C@@H](O)[C@H]1OC

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TYMP P19971 8/20 0.56
ADORA1 P30542 3/20 0.46
P2RY12 Q9H244 1/20 0.46
ADORA2A P29274 1/20 0.45
ADORA2B P29275 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23650062 0.91 TYMP (0.58) TYMPADORA1P2RY12ADORA2AADORA2B
SCHEMBL30091055 0.91 TYMP (0.58) TYMPADORA1P2RY12ADORA2AADORA2B
SCHEMBL7708120 0.91 TYMP (0.58) TYMPADORA1P2RY12ADORA2AADORA2B
SCHEMBL30396368 0.91 TYMP (0.58) TYMPADORA1P2RY12ADORA2AADORA2B
SCHEMBL6513309 0.91 TYMP (0.58) TYMPADORA1P2RY12ADORA2AADORA2B
SCHEMBL31676703 0.88 TYMP (0.60) TYMPADORA1MEN1KMT2A
SCHEMBL17417837 0.88 TYMP (0.48) TYMPADORA1P2RY12ADORA2AADORA2B
SCHEMBL6899475 0.87 TYMP (0.56) TYMPADORA1P2RY12ADORA2AADORA2B
SCHEMBL6898807 0.86 TYMP (0.55) TYMPADORA1P2RY12ADORA2AADORA2B
SCHEMBL6900160 0.86 TYMP (0.56) TYMPADORA1P2RY12ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9067964-B2 Complex and method for enhancing nuclear delivery OLIGOMER SCIENCES AB (SE) 2015-06-30 US disclosed
US-20110306138-A1 COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY OLIGOMER SCIENCES AB (SE) 2011-12-15 US disclosed
EP-2376518-A1 A COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY Avaris AB (SE) 2011-10-19 EP disclosed
WO-2010071587-A1 A COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY AVARIS AB (SE) 2010-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110306138-A1 COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY SNRPE, SNRPA, HNRNPH3 TYMP 379/4885ADORA1 2916/4885P2RY12 4345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.