SCHEMBL30396368

SCHEMBL30396368

COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(NC(=O)c5ccccc5)ncnc43)[C@H](OC)[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TYMP P19971 8/20 0.58
P2RY12 Q9H244 2/20 0.49
ADORA1 P30542 3/20 0.48
ADORA2A P29274 1/20 0.47
ADORA2B P29275 1/20 0.47
P2RY2 P41231 1/20 0.47
P2RY1 P47900 1/20 0.47
P2RY6 Q15077 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6513309 1.00 TYMP (0.58) TYMPP2RY12ADORA1ADORA2AADORA2B
SCHEMBL7708120 1.00 TYMP (0.58) TYMPP2RY12ADORA1ADORA2AADORA2B
SCHEMBL23650062 1.00 TYMP (0.58) TYMPP2RY12ADORA1ADORA2AADORA2B
SCHEMBL30091055 1.00 TYMP (0.58) TYMPP2RY12ADORA1ADORA2AADORA2B
SCHEMBL30689461 0.94 TYMP (0.58) TYMPP2RY12ADORA1ADORA2AADORA2B
SCHEMBL1040958 0.94 TYMP (0.56) TYMPP2RY12ADORA1ADORA2AADORA2B
SCHEMBL30200670 0.94 TYMP (0.56) TYMPP2RY12ADORA1ADORA2AADORA2B
SCHEMBL6834984 0.94 TYMP (0.56) TYMPP2RY12ADORA1ADORA2AADORA2B
SCHEMBL6900160 0.94 TYMP (0.56) TYMPP2RY12ADORA1ADORA2AADORA2B
SCHEMBL19493363 0.93 TYMP (0.67) TYMPP2RY12ADORA1P2RY2P2RY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741411-A2 OLIGONUCLEOTIDE PRODUCTION METHOD, AND NUCLEOSIDE, NUCLEOTIDE, OR OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2026-05-13 EP disclosed
EP-4720286-A2 SOD1-MODULATING COMPOSITIONS AND METHODS OF USE THEREOF Adarx Pharmaceuticals, Inc. (US) 2026-04-08 EP disclosed
US-20250312367-A1 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF ADARX PHARMACEUTICALS, INC. (US) 2025-10-09 US disclosed
EP-4522628-A2 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF Adarx Pharmaceuticals, Inc. (US) 2025-03-19 EP disclosed
US-20250026779-A1 ETHYL MODIFIED RNA CAPS AND METHODS OF USE MEDICI THERAPEUTICS, INC. 2025-01-23 US disclosed
WO-2024249328-A2 SOD1-MODULATING COMPOSITIONS AND METHODS OF USE THEREOF ADARX PHARMACEUTICALS, INC. (US) 2024-12-05 WO disclosed
WO-2024238396-A1 NMDA LIGAND CONJUGATED COMPOUNDS AND USES THEREOF ADARX PHARMACEUTICALS, INC. (US) 2024-11-21 WO disclosed
WO-2024220930-A2 MAPT-MODULATING COMPOSITIONS AND METHODS OF USE THEREOF ADARX PHARMACEUTICALS, INC. (US) 2024-10-24 WO disclosed
CN-117603287-A One-pot synthesis process of 3',3' -dimeric phosphoramidite 江苏申基生物科技有限公司 2024-02-27 CN disclosed
WO-2023220737-A2 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF ADARX PHARMACEUTICALS, INC. (US) 2023-11-16 WO disclosed
CN-116063365-A Method for preparing oligonucleotide and nucleoside, nucleotide or oligonucleotide 味之素株式会社 2023-05-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250026779-A1 ETHYL MODIFIED RNA CAPS AND METHODS OF USE RNGTT, RNMT, NSUN2 TYMP 535/4885P2RY12 3207/4885ADORA1 2145/4885
US-20250312367-A1 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF POLRMT, TARDBP, NSUN2 TYMP 77/4885P2RY12 2099/4885ADORA1 645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.