Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.34 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24831959 | 0.85 | SCN9A (0.39) | SCN9ASLC7A5MLYCDSLC1A3SLC1A2 | |
| SCHEMBL17152494 | 0.83 | SLC7A5 (0.52) | SCN9ASLC7A5MLYCDSLC1A3SLC1A2 | |
| SCHEMBL25530472 | 0.81 | DPP4 (0.36) | SLC7A5DPP4DPP8DPP9AAK1 | |
| SCHEMBL14623392 | 0.79 | DPP4 (0.44) | SCN9ASLC7A5MLYCDSLC1A3SLC1A2 | |
| SCHEMBL14624739 | 0.79 | DPP4 (0.44) | SCN9ASLC7A5MLYCDSLC1A3SLC1A2 | |
| SCHEMBL18774994 | 0.79 | BIRC2 (0.48) | — | |
| SCHEMBL18790951 | 0.79 | BIRC2 (0.48) | — | |
| SCHEMBL21230224 | 0.79 | MLYCD (0.36) | MLYCDMMP1MMP3MMP9MMP2 | |
| Hydrochloric Acid SCHEMBL18762558 | 0.78 | BIRC2 (0.47) | — | |
| Hydrochloric Acid SCHEMBL18762561 | 0.78 | BIRC2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3364958-B1 | MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF | NAVITOR PHARM INC (US) | 2023-01-04 | — | — | EP | disclosed |