⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24834792 | 1.00 | — | — | |
| SCHEMBL29785689 | 1.00 | — | — | |
| SCHEMBL29785438 | 1.00 | — | — | |
| SCHEMBL29785485 | 0.90 | PDE10A (0.31) | — | |
| SCHEMBL24834881 | 0.90 | PDE10A (0.31) | — | |
| SCHEMBL28786353 | 0.90 | PDE10A (0.31) | — | |
| SCHEMBL24834762 | 0.90 | PDE10A (0.31) | — | |
| SCHEMBL28786386 | 0.86 | KDR (0.32) | — | |
| SCHEMBL24835002 | 0.86 | PLAT (0.39) | — | |
| SCHEMBL24835003 | 0.86 | PLAT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002396-A1 | THERAPEUTIC COMPOUNDS | GENENTECH, INC. (US) | 2023-01-05 | — | — | US | disclosed |
| US-20230002396-A1 | THERAPEUTIC COMPOUNDS | GENENTECH, INC. (US) | 2023-01-05 | — | — | US | disclosed |
| CN-114786778-A | Therapeutic compounds | 基因泰克公司 | 2022-07-22 | — | — | CN | disclosed |