Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27212321 | 0.85 | CYP1A2 (0.67) | CYP1A2CYP2C9CYP2C19KDM4EMEN1 | |
| SCHEMBL30778024 | 0.82 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19KDM4EMEN1 | |
| SCHEMBL23733256 | 0.82 | KDM4E (0.56) | KDM4EMEN1KMT2AAKR1C3SMN1; SMN2 | |
| SCHEMBL23283027 | 0.77 | KDM4E (0.51) | KDM4EMEN1KMT2AAKR1C3SMN1; SMN2 | |
| SCHEMBL23283044 | 0.76 | MEN1 (0.43) | CYP1A2CYP2C9CYP2C19KDM4EMEN1 | |
| SCHEMBL23283047 | 0.72 | KDM4E (0.52) | KDM4EMEN1KMT2AAKR1C3SMN1; SMN2 | |
| SCHEMBL23277135 | 0.72 | ADRB1 (0.57) | KDM4EAKR1C3ALDH1A1LMNA | |
| SCHEMBL23283028 | 0.70 | KDM4E (0.52) | KDM4EMEN1KMT2AAKR1C3SMN1; SMN2 | |
| SCHEMBL28396664 | 0.68 | ADRB1 (0.71) | KDM4EAKR1C3ALDH1A1LMNA | |
| SCHEMBL23064287 | 0.67 | GAA (0.67) | CYP1A2CYP2C9CYP2C19KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023276828-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING KIDNEY INJURY, AND AUTOPHAGY ACTIVATOR | 国立大学法人大阪大学 | 2023-01-05 | — | — | WO | disclosed |