Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24835159 | 0.85 | NR1H2 (0.51) | MEN1KMT2ATSHRMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL27900963 | 0.84 | TSHR (0.58) | MEN1KMT2ATSHRMAPTSMN1; SMN2 | |
| SCHEMBL11677518 | 0.83 | SMN1; SMN2 (0.52) | MEN1KMT2ATSHRMAPTSMN1; SMN2 | |
| SCHEMBL11676189 | 0.81 | MAPT (0.65) | MEN1KMT2ATSHRMAPTSMN1; SMN2 | |
| SCHEMBL24835163 | 0.80 | KDM4E (0.61) | CYP4A11MGLLMAPTKDM4EALDH1A1 | |
| SCHEMBL24835214 | 0.79 | CYP4A11 (0.58) | MEN1KMT2ACYP4A11CYP4F2TSHR | |
| SCHEMBL65794 | 0.78 | MAPT (0.61) | MEN1KMT2ATSHRMAPTSMN1; SMN2 | |
| SCHEMBL1928912 | 0.78 | TSHR (0.67) | CYP4A11MGLLCYP4F2TSHRMAPT | |
| SCHEMBL10524794 | 0.78 | TSHR (0.64) | TSHRNR1H2NR1H3 | |
| SCHEMBL6256717 | 0.78 | ESRRG (0.50) | MEN1KMT2AMGLLTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |