Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | ESRRG | P62508 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | ESRRB | O95718 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24835233 | 0.85 | MEN1 (0.51) | NR1H2NR1H3ALDH1A1ESRRGTSHR | |
| SCHEMBL10524794 | 0.83 | TSHR (0.64) | NR1H2NR1H3TSHRAOC3 | |
| SCHEMBL24835780 | 0.82 | KARS1 (0.47) | ALDH1A1RARBMEN1RARAMAPT | |
| SCHEMBL27747274 | 0.81 | PPARG (0.50) | ALDH1A1RARBMEN1RARAMAPT | |
| SCHEMBL7774965 | 0.80 | HDAC1 (0.49) | ALDH1A1RARBTSHRMEN1KMT2A | |
| SCHEMBL11074121 | 0.80 | CNR2 (0.51) | ALDH1A1RARBESRRGTSHRMEN1 | |
| SCHEMBL11212593 | 0.79 | KCNH2 (0.53) | NR1H2NR1H3TSHRAOC3 | |
| SCHEMBL28904547 | 0.79 | TSHR (0.55) | NR1H2NR1H3ALDH1A1TSHRMAPT | |
| SCHEMBL1348061 | 0.78 | ALDH1A1 (0.57) | ALDH1A1RARBTSHRMEN1RARA | |
| SCHEMBL64440 | 0.77 | MEN1 (0.56) | ALDH1A1RARBTSHRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |