Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PTPRB | P23467 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20347162 | 0.82 | HPGD (0.50) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20350802 | 0.82 | PTPN1 (0.44) | HPGDLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL20333729 | 0.79 | ITGB1 (0.40) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20350468 | 0.79 | TSHR (0.47) | SMN1; SMN2ALDH1A1PTPRBPTPN2PTPN1 | |
| SCHEMBL20333376 | 0.78 | KMT2A (0.46) | KDM4ESMN1; SMN2ALDH1A1PTPRBRECQL | |
| SCHEMBL22216480 | 0.77 | RAB9A (0.49) | KDM4EHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL21602081 | 0.77 | PDCD1 (0.45) | HPGDLMNAALDH1A1HTT | |
| SCHEMBL20350676 | 0.75 | FFAR1 (0.47) | KDM4ELMNAALDH1A1NR1H4NPSR1 | |
| SCHEMBL20333378 | 0.75 | PTPN1 (0.43) | PTPN1 | |
| SCHEMBL24836153 | 0.75 | PARP10 (0.46) | KDM4ESMN1; SMN2ALDH1A1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002437-A1 | ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF | ANTENGENE THERAPEUTICS LIMITED (CN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002437-A1 | ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF | NT5E, ENTPD5, NT5C2 | KDM4E 2596/4885HPGD 172/4885LMNA 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.