Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28326928 | 0.89 | TSHR (0.43) | ALDH1A1TSHRHTR2ASIGMAR1RECQL | |
| SCHEMBL922759 | 0.85 | ALDH1A1 (0.67) | GFERMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL26463210 | 0.84 | MAOB (0.46) | GFERMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL421341 | 0.82 | GFER (0.77) | GFERMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL12110702 | 0.82 | GFER (0.77) | GFERMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL2914010 | 0.82 | GFER (0.77) | GFERMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL525926 | 0.82 | — | — | |
| SCHEMBL7018335 | 0.80 | TAAR1 (0.56) | MAOBALDH1A1TDP1HTR2ALOXL2 | |
| SCHEMBL6363967 | 0.80 | CYP3A4 (0.74) | GFERMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL6362172 | 0.80 | CYP3A4 (0.74) | GFERMAOBALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278604-A1 | PHARMACOLOGICAL AGENTS FOR TREATING OPHTHALMIC DISEASES | PLEX PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |