Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22071946 | 0.93 | ELANE (0.47) | ELANECFDKMT2AATMBACE1 | |
| SCHEMBL22071932 | 0.92 | ELANE (0.40) | ELANECFDKMT2AATMBACE1 | |
| SCHEMBL22031974 | 0.92 | ELANE (0.48) | ELANECFDKMT2AATMBACE1 | |
| SCHEMBL24836157 | 0.89 | ELANE (0.48) | ELANEKMT2AATMBACE1SMN1; SMN2 | |
| SCHEMBL22353023 | 0.88 | SMN1; SMN2 (0.50) | ELANEKMT2AATMBACE1SMN1; SMN2 | |
| SCHEMBL25936911 | 0.88 | SMN1; SMN2 (0.50) | ELANEKMT2AATMBACE1SMN1; SMN2 | |
| SCHEMBL24836189 | 0.88 | ELANE (0.39) | ELANECFDKMT2AATMBACE1 | |
| SCHEMBL22071933 | 0.87 | CFD (0.54) | ELANECFDKMT2AATMBACE1 | |
| SCHEMBL22073547 | 0.86 | ELANE (0.41) | ELANECFDKMT2AATMBACE1 | |
| SCHEMBL25573719 | 0.86 | SMN1; SMN2 (0.42) | ELANECFDKMT2AATMBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023208801-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-11-02 | — | — | WO | disclosed |
| US-11739266-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-11739266-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-20230183571-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-06-15 | — | — | US | disclosed |
| US-20230183571-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-06-15 | — | — | US | disclosed |
| EP-4194529-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | Merck Patent GmbH (DE) | 2023-06-14 | — | — | EP | disclosed |
| US-20230002678-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2023-01-05 | — | — | US | disclosed |