SCHEMBL2483784

SCHEMBL2483784

C1=C2SCC=C2c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.33
DRD2 P14416 2/20 0.32
DRD4 P21917 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29529446 1.00 S100A4 (0.33) S100A4DRD2DRD4
Naphthalene SCHEMBL28648756 0.94 S100A4 (0.31) S100A4DRD2DRD4
Thiophene SCHEMBL29107340 0.91
SCHEMBL28893496 0.81
SCHEMBL28907381 0.77
SCHEMBL29048131 0.73 S100A4 (0.31) S100A4
SCHEMBL10354666 0.69 ABCG2 (0.39) S100A4DRD2DRD4
SCHEMBL5886591 0.69 ABCG2 (0.39) S100A4DRD2DRD4
SCHEMBL9118090 0.66 ABCG2 (0.38) S100A4DRD2DRD4
SCHEMBL2918505 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1923387-B1 ACYLGUANIDINE DERIVATIVE OR SALT THEREOF ASTELLAS PHARMA INC (JP) 2011-10-19 EP claimed
CN-120794952-A Synthetic benzocyclopentene thiophene compound method 云南大学 2025-10-17 CN disclosed
CN-114573551-A Preparation method of benzo-cyclopentenothiophene compound 浙大宁波理工学院 2022-06-03 CN disclosed