SCHEMBL24839632

SCHEMBL24839632

c1ccc(C2=C(c3ccccc3)c3cccc4[nH]c5ccc6cccc2c6c5c34)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 10/20 0.51
CCND1 P24385 10/20 0.51
CCNB2 O95067 1/20 0.40
CCNE2 O96020 1/20 0.40
CDK1 P06493 1/20 0.40
CCNB1 P14635 1/20 0.40
CCNE1 P24864 1/20 0.40
CDK2 P24941 1/20 0.40
CCNB3 Q8WWL7 1/20 0.40
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
PLK4 O00444 1/20 0.37
MAPK9 P45984 1/20 0.37
LIMK1 P53667 1/20 0.37
CLK4 Q9HAZ1 1/20 0.37
AKT3 Q9Y243 1/20 0.37
MAPK1 P28482 3/20 0.36
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
ATM Q13315 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25505438 0.90 CDK4 (0.44) CDK4CCND1CCNB2CCNE2CDK1
SCHEMBL25505436 0.90 CDK4 (0.46) CDK4CCND1CCNB2CCNE2CDK1
SCHEMBL24839685 0.86 CDK4 (0.43) CDK4CCND1CCNB2CCNE2CDK1
SCHEMBL21630342 0.84 ALDH1A1 (0.54) CDK4CCND1CCNB2CCNE2CDK1
SCHEMBL23024713 0.78 CDK4 (0.46) CDK4CCND1CCNB2CCNE2CDK1
SCHEMBL24245725 0.78 ALDH1A1 (0.48) CDK4CCND1CCNB2CCNE2CDK1
SCHEMBL4590261 0.78 ALDH1A1 (0.59) RAB9AMAPK1ALDH1A1TSHRATM
SCHEMBL23945224 0.77 CDK4 (0.71) CDK4CCND1CCNB2CCNE2CDK1
SCHEMBL21650714 0.76 CDK4 (0.47) CDK4CCND1CCNB2CCNE2CDK1
SCHEMBL21765723 0.76 CDK4 (0.60) CDK4CCND1CCNB2CCNE2CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277313-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2023-01-05 WO disclosed