Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 13/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.46 |
| ▸ | RORA | P35398 | 1/20 | 0.46 |
| ▸ | RORB | Q92753 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24840251 | 0.93 | RORC (0.53) | RORCNR1I2RORARORBNPC1 | |
| SCHEMBL24839958 | 0.91 | CYP2C9 (0.52) | RORCNR1I2RORARORBNPC1 | |
| SCHEMBL24840402 | 0.91 | RORC (0.51) | RORCNR1I2RORARORBNPC1 | |
| SCHEMBL24840258 | 0.90 | RORC (0.57) | RORCNR1I2RORARORB | |
| SCHEMBL24840212 | 0.88 | RORC (0.49) | RORCNR1I2RORARORBNPC1 | |
| SCHEMBL24840418 | 0.88 | RORC (0.49) | RORCNR1I2RORARORBNPC1 | |
| SCHEMBL24840211 | 0.87 | RORC (0.59) | RORCNR1I2RORARORBPKM | |
| SCHEMBL24840240 | 0.85 | RORC (0.57) | RORCNR1I2RORARORB | |
| SCHEMBL24287236 | 0.85 | RORC (0.61) | RORCNR1I2RORARORB | |
| SCHEMBL24839969 | 0.85 | RORC (0.57) | RORCNR1I2RORARORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274396-A1 | BENZAZEPINE HETEROCYCLIC COMPOUND AND APPLICATION THEREOF IN MEDICINE | 广东东阳光药业有限公司 | 2023-01-05 | — | — | WO | disclosed |