SCHEMBL24840345

SCHEMBL24840345

CC1(C)c2ccccc2-c2ccc(N(c3ccc4c(c3)oc3ccccc34)c3cccc(-c4ccccc4)c3-c3cccc4c3-c3ccccc3C4(C)C)cc21

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALK Q9UM73 8/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20799817 0.94 MEN1 (0.32) MEN1THRBRECQLBLMKMT2A
SCHEMBL24840338 0.94 ALK (0.34) ALK
SCHEMBL24856439 0.94 ALK (0.33) MEN1THRBRECQLBLMKMT2A
SCHEMBL24840199 0.94 MEN1 (0.34) MEN1THRBRECQLBLMKMT2A
SCHEMBL24839589 0.93 MEN1 (0.30) MEN1THRBRECQLBLMKMT2A
SCHEMBL24840341 0.91 ALK (0.32) ALK
SCHEMBL25577976 0.91 ALK (0.33) MEN1THRBRECQLBLMKMT2A
SCHEMBL27017533 0.91 MEN1 (0.33) MEN1THRBRECQLBLMKMT2A
SCHEMBL25145421 0.91 ALK (0.35) MEN1KMT2AALK
SCHEMBL24839582 0.91 ALK (0.31) MEN1THRBRECQLBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023273998-A1 COMPOUND AND APPLICATION THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE 北京鼎材科技有限公司 2023-01-05 WO disclosed