SCHEMBL24856439

SCHEMBL24856439

CC1(C)c2ccccc2-c2c(-c3c(-c4ccccc4)cccc3N(c3ccccc3)c3ccc4c(c3)oc3ccccc34)cccc21

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 3/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
THRB P10828 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
AHR P35869 1/20 0.30
PGR P06401 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25577976 0.95 ALK (0.33) ALKMEN1KMT2ATHRBRECQL
SCHEMBL25577981 0.94 PGR (0.31) ALKMEN1KMT2ATHRBRECQL
SCHEMBL24840345 0.94 MEN1 (0.33) ALKMEN1KMT2ATHRBRECQL
SCHEMBL24839992 0.92 PGR (0.32) ALKMEN1KMT2ATHRBRECQL
SCHEMBL25577982 0.91 PGR (0.31) ALKMEN1KMT2ATHRBRECQL
SCHEMBL24856326 0.91 ALK (0.33) ALKMEN1KMT2ATHRBRECQL
SCHEMBL24839598 0.91 ALK (0.33) ALK
SCHEMBL25449923 0.91 MEN1 (0.33) ALKMEN1KMT2ATHRBRECQL
SCHEMBL19596024 0.91 MEN1 (0.33) ALKMEN1KMT2ATHRBRECQL
SCHEMBL26599705 0.90 MEN1 (0.33) ALKMEN1KMT2ATHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023273997-A1 ORGANIC COMPOUND AND APPLICATION THEREOF 北京鼎材科技有限公司 2023-01-05 WO disclosed