Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108707 | 1.00 | IL1B (0.78) | IL1BNLRP3 | |
| SCHEMBL29696881 | 1.00 | IL1B (0.78) | IL1BNLRP3 | |
| SCHEMBL29275873 | 1.00 | IL1B (0.78) | IL1BNLRP3 | |
| SCHEMBL24574982 | 1.00 | IL1B (0.78) | IL1BNLRP3 | |
| SCHEMBL29275765 | 0.97 | IL1B (0.73) | IL1BNLRP3 | |
| Formic Acid SCHEMBL29276027 | 0.96 | IL1B (0.71) | IL1BNLRP3 | |
| SCHEMBL30349828 | 0.95 | IL1B (0.73) | IL1BNLRP3 | |
| SCHEMBL30349720 | 0.95 | IL1B (0.73) | IL1BNLRP3 | |
| SCHEMBL28961890 | 0.94 | IL1B (0.68) | IL1BNLRP3 | |
| SCHEMBL28961887 | 0.94 | IL1B (0.68) | IL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881401-A | NLRP3 modulators | 祖玛珍生物科学有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-116969920-A | Fused pyridazine derivative, preparation method and medical application thereof | 上海辉启生物医药科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116390914-A | Pyridazine-containing compound and medical application thereof | 上海拓界生物医药科技有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-116102535-A | Nitrogen-containing compound, preparation method and application thereof | 索智生物科技（浙江）有限公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |
| WO-2023278438-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD (US) | 2023-01-05 | — | — | WO | disclosed |
| CN-115433163-A | NLRP3 inflammasome inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |