Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2485103 | 0.86 | CCR2 (0.62) | CCR2KCNH2 | |
| SCHEMBL2482688 | 0.86 | CCR2 (0.54) | CCR2KCNH2 | |
| SCHEMBL2483850 | 0.86 | CCR2 (0.51) | CCR2KCNH2 | |
| SCHEMBL2484276 | 0.85 | CCR2 (0.55) | CCR2KCNH2 | |
| SCHEMBL2481358 | 0.85 | CCR2 (0.67) | CCR2KCNH2 | |
| SCHEMBL3415338 | 0.85 | CCR2 (0.55) | CCR2KCNH2 | |
| SCHEMBL3347918 | 0.84 | CCR2 (0.67) | CCR2KCNH2 | |
| SCHEMBL3719908 | 0.84 | CCR2 (0.61) | CCR2KCNH2 | |
| SCHEMBL2485172 | 0.84 | CCR2 (0.65) | CCR2KCNH2 | |
| SCHEMBL2481121 | 0.83 | CCR2 (0.68) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376475-A1 | 4-AZETIDINYL-1-HETEROARYL-CYCLOHEXANOL ANTAGONISTS OF CCR2 | Janssen Pharmaceutica N.V. (BE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010068663-A1 | 4-AZETIDINYL-1-HETEROARYL-CYCLOHEXANOL ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2010-06-17 | — | — | WO | disclosed |