Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | IDE | P14735 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HLCS | P50747 | 4/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990790 | 0.94 | TDP1 (0.56) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL30958922 | 0.85 | TDP1 (0.58) | TDP1PKMMEN1ABL1LMNA | |
| Trifluoroacetic Acid SCHEMBL2520452 | 0.83 | PRSS1 (0.63) | TDP1PKMMEN1ABL1LMNA | |
| Trifluoroacetic Acid SCHEMBL1163788 | 0.83 | PRSS1 (0.63) | TDP1PKMMEN1ABL1LMNA | |
| Trifluoroacetic Acid SCHEMBL31004018 | 0.80 | FOLH1 (0.55) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL6040739 | 0.79 | TDP1 (0.67) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL28163095 | 0.78 | TDP1 (0.65) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL1405877 | 0.78 | FOLH1 (0.56) | TDP1PKMMEN1ABL1LMNA | |
| Hydrochloric Acid SCHEMBL9073700 | 0.78 | TDP1 (0.65) | TDP1PKMMEN1ABL1LMNA | |
| Biotin SCHEMBL31708327 | 0.78 | TDP1 (0.85) | TDP1PKMMEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036684-A1 | COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS | SATORI PHARMACEUTICALS, INC (US) | 2013-03-14 | — | — | WO | disclosed |
| EP-2542085-A1 | COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS | Satori Pharmaceuticals, Inc. (US) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011109657-A1 | COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS | SATORI PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |