Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HLCS | P50747 | 6/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2484254 | 0.94 | TDP1 (0.52) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL30958922 | 0.91 | TDP1 (0.58) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL6040739 | 0.84 | TDP1 (0.67) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL28163095 | 0.83 | TDP1 (0.65) | TDP1PKMMEN1ABL1LMNA | |
| Hydrochloric Acid SCHEMBL9073700 | 0.83 | TDP1 (0.65) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL2536441 | 0.82 | TDP1 (0.62) | TDP1PKMMEN1ABL1LMNA | |
| Hydrochloric Acid SCHEMBL3417755 | 0.81 | TDP1 (0.61) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL1405877 | 0.81 | FOLH1 (0.56) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL7262622 | 0.81 | TDP1 (0.53) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL24670280 | 0.81 | PRSS1 (0.68) | TDP1PKMMEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274325-B1 | USING A FAB'-BIOTIN MATERIAL AND AGGLUTINATABLE PARTICLES WHICH CARRY STREPTAVIDIN OR AVIDIN | BOEHRINGER MANNHEIM GMBH (DE) | 2001-08-14 | — | — | US | disclosed |
| EP-0632810-B1 | NEW BIOTINYLATION REAGENT | ROCHE DIAGNOSTICS GMBH (DE) | 2000-11-29 | — | — | EP | disclosed |
| EP-0749435-B1 | INTERFERENCE SUPPRESSION AGENT FOR USE IN IMMUNO ASSAYING | ROCHE DIAGNOSTICS GMBH (DE) | 2000-10-11 | — | — | EP | disclosed |
| EP-0697021-B1 | PHOTO-ACTIVATABLE BIOTIN DERIVATIVES AND THEIR USE IN SUPPRESSING INTERFERENCE IN IMMUNO ASSAYING | ROCHE DIAGNOSTICS GMBH (DE) | 2000-07-05 | — | — | EP | disclosed |
| US-5952185-A | ACTIVE CENTER OF AVIDIN OR STREPAVIDIN COUPLED TO BIOTIN | BOEHRINGER MANNHEIM GMBH (DE) | 1999-09-14 | — | — | US | disclosed |
| US-5863740-A | USING AVIDIN OR STREPTAVIDIN DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5763191-A | BINDING MATRIX | BOEHRINGER MANNHEIM GMBH (DE) | 1998-06-09 | — | — | US | disclosed |
| EP-0749435-A1 | INTERFERENCE SUPPRESSION AGENT FOR USE IN IMMUNO ASSAYING | Roche Diagnostics GmbH (DE) | 1996-12-27 | — | — | EP | disclosed |
| EP-0515615-B1 | UNIVERSAL BINDING FILM | BOEHRINGER MANNHEIM GMBH (DE) | 1996-09-04 | — | — | EP | disclosed |
| US-5521319-A | Biotinylation reagent and method of use thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1996-05-28 | — | — | US | disclosed |
| EP-0697021-A1 | PHOTO-ACTIVATABLE BIOTIN DERIVATIVES AND THEIR USE IN SUPPRESSING INTERFERENCE IN IMMUNO ASSAYING | Roche Diagnostics GmbH (DE) | 1996-02-21 | — | — | EP | disclosed |
| WO-1995023801-A1 | INTERFERENCE SUPPRESSION AGENT FOR USE IN IMMUNO ASSAYING | BOEHRINGER MANNHEIM GMBH (DE) | 1995-09-08 | — | — | WO | disclosed |
| WO-1995023800-A1 | PHOTO-ACTIVATABLE BIOTIN DERIVATIVES AND THEIR USE IN SUPPRESSING INTERFERENCE IN IMMUNO ASSAYING | BOEHRINGER MANNHEIM GMBH (DE) | 1995-09-08 | — | — | WO | disclosed |
| EP-0632810-A1 | NEW BIOTINYLATION REAGENT | Roche Diagnostics GmbH (DE) | 1995-01-11 | — | — | EP | disclosed |
| WO-1994017072-A1 | NEW BIOTINYLATION REAGENT | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |
| EP-0515615-A1 | UNIVERSAL BINDING FILM. | BOEHRINGER MANNHEIM GMBH (DE) | 1992-12-02 | — | — | EP | disclosed |
| WO-1992010757-A1 | UNIVERSAL BINDING FILM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-06-25 | — | — | WO | disclosed |