SCHEMBL2484356

SCHEMBL2484356

CC(C)Cc1cc(O)c(C(C)(C)C)cc1Sc1cc(C(C)(C)C)c(O)cc1CC(C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 8/20 0.54
ALDH1A1 P00352 4/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
TP53 P04637 3/20 0.54
CYP3A4 P08684 2/20 0.54
HIF1A Q16665 2/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
CYP1A2 P05177 2/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ATP2A2 P16615 1/20 0.45
ATP2A3 Q93084 1/20 0.45
CYP2C9 P11712 3/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C19 P33261 2/20 0.40
GABRA1 P14867 2/20 0.39
GABRB2 P47870 2/20 0.39
LMNA P02545 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7160909 0.88 ALOX15 (0.43) ALOX15ALDH1A1SMN1; SMN2TP53CYP3A4
SCHEMBL10015714 0.83 ALOX15 (0.69) ALOX15ALDH1A1SMN1; SMN2TP53CYP3A4
SCHEMBL12443089 0.82 ALOX15 (0.58) ALOX15ALDH1A1SMN1; SMN2TP53CYP3A4
SCHEMBL29517048 0.82 ALOX15 (0.61) ALOX15ALDH1A1SMN1; SMN2TP53CYP3A4
SCHEMBL2484931 0.82 ALOX15 (0.61) ALOX15ALDH1A1SMN1; SMN2TP53CYP3A4
SCHEMBL27559201 0.79 ALOX15 (0.58) ALOX15ALDH1A1SMN1; SMN2TP53CYP3A4
SCHEMBL2483068 0.78 ALOX15 (0.56) ALOX15ALDH1A1SMN1; SMN2TP53CYP3A4
SCHEMBL21537522 0.76 ALOX15 (0.49) ALOX15ALDH1A1SMN1; SMN2TP53CYP3A4
SCHEMBL2477818 0.75 ALOX15 (0.53) ALOX15ALDH1A1SMN1; SMN2TP53CYP3A4
SCHEMBL12443051 0.74 HSPA5 (0.51) ALOX15ALDH1A1SMN1; SMN2TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1947725-B1 Polymer electrolyte composition and fuel cell SUMITOMO CHEMICAL CO (JP) 2011-10-19 EP disclosed
EP-1947725-A2 Polymer electrolyte composition and fuel cell Sumitomo Chemical Company, Limited (JP) 2008-07-23 EP disclosed
US-20060257706-A1 POLYMER ELECTROLYTE COMPOSITION AND FUEL CELL HIDAKA YASUAKI 2006-11-16 US disclosed
EP-1289041-A2 Polymer electrolyte composition and fuel cell SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-05 EP disclosed