Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13455119 | 0.80 | NPY5R (0.41) | NPY5RLCKJAK3 | |
| SCHEMBL23714592 | 0.77 | MAPK1 (0.43) | NPY5RLCKJAK3 | |
| SCHEMBL24629551 | 0.77 | HTR2A (0.37) | NPY5RLCKJAK3 | |
| SCHEMBL17001889 | 0.75 | CHRM2 (0.41) | NPY5R | |
| SCHEMBL25045258 | 0.75 | ALDH1A1 (0.35) | — | |
| SCHEMBL15448411 | 0.73 | NPY5R (0.38) | NPY5R | |
| SCHEMBL10801437 | 0.72 | MAPK1 (0.39) | NPY5RLCKJAK3 | |
| SCHEMBL21222493 | 0.72 | MAPK1 (0.39) | NPY5RLCKJAK3 | |
| SCHEMBL10801442 | 0.72 | MAPK1 (0.39) | NPY5RLCKJAK3 | |
| SCHEMBL2853627 | 0.72 | TP53 (0.42) | NPY5REGFRLCKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023275199-A1 | MACROCYCLIC TAK1 INHIBITORS | AQILION AB (SE) | 2023-01-05 | — | — | WO | disclosed |