Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | FADS1 | O60427 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24844854 | 0.86 | KDM4C (0.38) | KDM5BKDM5AKDM4CPHF8PANK3 | |
| SCHEMBL24844790 | 0.79 | FFAR1 (0.39) | BRD4KDM5BKDM5AKDM4CHRH3 | |
| SCHEMBL24845188 | 0.79 | FFAR1 (0.39) | BRD4KDM5BKDM5AKDM4CHRH3 | |
| SCHEMBL24844840 | 0.79 | FFAR1 (0.39) | BRD4KDM5BKDM5AKDM4CHRH3 | |
| SCHEMBL24845137 | 0.79 | FFAR1 (0.39) | BRD4KDM5BKDM5AKDM4CHRH3 | |
| SCHEMBL24844839 | 0.78 | BRD4 (0.41) | BRD4KDM5BKDM5AKDM4CFADS1 | |
| SCHEMBL24844748 | 0.76 | CYP11B1 (0.45) | — | |
| SCHEMBL24844792 | 0.74 | PHF8 (0.51) | BRD4KDM5BKDM5AKDM4CPHF8 | |
| SCHEMBL24845134 | 0.74 | PDE2A (0.32) | KDM5BKDM5AKDM4CPANK3PDE2A | |
| SCHEMBL11481614 | 0.71 | CYP11B1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274257-A1 | IMIDAZOLE COMPOUND, AND INTERMEDIATE AND APPLICATION THEREOF | 诸葛国琴 | 2023-01-05 | — | — | WO | disclosed |