SCHEMBL24844792

SCHEMBL24844792

Fc1cn(Cc2ccccc2Cl)cn1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PHF8 Q9UPP1 4/20 0.51
BRD4 O60885 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
KDM2A Q9Y2K7 1/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
KDM4C Q9H3R0 2/20 0.45
KDM5A P29375 1/20 0.45
KDM5B Q9UGL1 1/20 0.45
KDM2B Q8NHM5 1/20 0.44
CYP19A1 P11511 1/20 0.43
POLB P06746 1/20 0.41
SIGMAR1 Q99720 1/20 0.40
CYP2A13 Q16696 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24844782 0.83 PHF8 (0.53) PHF8SMN1; SMN2KDM2ALMNAHTT
SCHEMBL24845157 0.83 KDM5B (0.52) BRD4LMNAKDM4CKDM5AKDM5B
SCHEMBL6529657 0.80 PHF8 (0.51) PHF8SMN1; SMN2KDM2ALMNAHTT
SCHEMBL24844768 0.80 CYP11B1 (0.53) PHF8BRD4SMN1; SMN2LMNAHTT
SCHEMBL6529662 0.80 PHF8 (0.54) PHF8SMN1; SMN2KDM2ALMNAHTT
SCHEMBL19936854 0.79 HPGDS (0.51) PHF8BRD4RAB9AKDM4CKDM5A
SCHEMBL10795248 0.79 PHF8 (0.50) PHF8SMN1; SMN2KDM2ALMNAHTT
SCHEMBL3727754 0.75 BRD4 (0.48) BRD4KDM4CKDM5AKDM5BCYP19A1
SCHEMBL9714098 0.74 LMNA (0.50) PHF8SMN1; SMN2KDM2ALMNAHTT
SCHEMBL24845293 0.74 BRD4 (0.41) PHF8BRD4SMN1; SMN2KDM2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023274257-A1 IMIDAZOLE COMPOUND, AND INTERMEDIATE AND APPLICATION THEREOF 诸葛国琴 2023-01-05 WO disclosed