Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24846480 | 0.81 | ENPP1 (1.00) | ENPP1MAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL24846430 | 0.81 | CYP2C19 (0.56) | ENPP1MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL24846278 | 0.79 | ENPP1 (0.68) | ENPP1MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL24846260 | 0.78 | ENPP1 (0.64) | ENPP1MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL24846498 | 0.77 | ENPP1 (0.82) | ENPP1ALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL24846382 | 0.77 | ENPP1 (0.84) | ENPP1MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL24847265 | 0.76 | ENPP1 (0.80) | ENPP1MAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL24846493 | 0.76 | ENPP1 (0.73) | ENPP1ALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL24846557 | 0.75 | ENPP1 (0.79) | ENPP1MAPTALDH1A1KMT2ACYP1A2 | |
| SCHEMBL965696 | 0.75 | KMT2A (0.70) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002387-A1 | 2-AMINO-S6-SUBSTITUTED THIOPURINE COMPOUNDS AS INHIBITORS OF THE ENPP1 PROTEIN | ATEN PORUS LIFESCIENCES PVT. LTD. (IN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002387-A1 | 2-AMINO-S6-SUBSTITUTED THIOPURINE COMPOUNDS AS INHIBITORS OF THE ENPP1 PROTEIN | ENPP1, ENPP3, PNP | ENPP1 1/4885MAPT 2774/4885RAB9A 1241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.