Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24847994 | 0.89 | KMT2A (0.38) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL24847993 | 0.88 | MEN1 (0.37) | MEN1KMT2ALMNAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL31161458 | 0.86 | MEN1 (0.40) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL27225016 | 0.86 | MEN1 (0.42) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL27166458 | 0.85 | MEN1 (0.37) | MEN1KMT2ALMNAHCRTR2HCRTR1 | |
| SCHEMBL24607672 | 0.84 | LMNA (0.40) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL29751507 | 0.84 | LMNA (0.40) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL31701224 | 0.84 | MEN1 (0.46) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL23832587 | 0.83 | HCRTR2 (0.40) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL23842066 | 0.83 | HCRTR2 (0.40) | MEN1KMT2ALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278759-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |