Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489804 | 1.00 | LMNA (0.54) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL2484741 | 1.00 | LMNA (0.54) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL598289 | 0.88 | LMNA (0.52) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL12956362 | 0.87 | — | — | |
| SCHEMBL4776978 | 0.86 | LMNA (0.50) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL11441647 | 0.84 | LMNA (0.48) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL29067829 | 0.84 | LMNA (0.54) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL18727407 | 0.84 | LMNA (0.38) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL21029957 | 0.82 | — | — | |
| SCHEMBL4781049 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178686-B2 | Process for preparing optically active aminopentane derivative, intermediate and process for preparing intermediate | FUJIMOTO CO., LTD. (JP) | 2012-05-15 | — | — | US | claimed |
| EP-1905760-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE IN THE PROCESS AND PROCESS FOR PRODUCTION OF THE INTERMEDIATE | FUJIMOTO CO LTD (JP) | 2011-10-26 | — | — | EP | claimed |
| US-20100324300-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE AND PROCESS FOR PREPARING INTERMEDIATE | YONEDA FUMIO | 2010-12-23 | — | — | US | claimed |
| US-7807840-B2 | Process for preparing optically active aminopentane derivative, intermediate and process for preparing intermediate | FUJIMOTO CO., LTD. (JP) | 2010-10-05 | — | — | US | claimed |
| US-20090124813-A1 | Process for Preparing Optically Active Aminopentane Derivative, Intermediate and Process for Preparing Intermediate | FUJIMOTO CO., LTD. (JP) | 2009-05-14 | — | — | US | claimed |
| EP-1905760-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE IN THE PROCESS AND PROCESS FOR PRODUCTION OF THE INTERMEDIATE | Fujimoto Co., Ltd. (JP) | 2008-04-02 | — | — | EP | claimed |
| US-8178686-B2 | Process for preparing optically active aminopentane derivative, intermediate and process for preparing intermediate | FUJIMOTO CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178686-B2 | Process for preparing optically active aminopentane derivative, intermediate and process for preparing intermediate | FUJIMOTO CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178686-B2 | Process for preparing optically active aminopentane derivative, intermediate and process for preparing intermediate | FUJIMOTO CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| EP-1905760-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE IN THE PROCESS AND PROCESS FOR PRODUCTION OF THE INTERMEDIATE | FUJIMOTO CO LTD (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-20100324300-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE AND PROCESS FOR PREPARING INTERMEDIATE | YONEDA FUMIO | 2010-12-23 | — | — | US | disclosed |
| US-20100324300-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE AND PROCESS FOR PREPARING INTERMEDIATE | YONEDA FUMIO | 2010-12-23 | — | — | US | disclosed |
| US-20100324300-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE AND PROCESS FOR PREPARING INTERMEDIATE | YONEDA FUMIO | 2010-12-23 | — | — | US | disclosed |
| US-7807840-B2 | Process for preparing optically active aminopentane derivative, intermediate and process for preparing intermediate | FUJIMOTO CO., LTD. (JP) | 2010-10-05 | — | — | US | disclosed |
| US-20090124813-A1 | Process for Preparing Optically Active Aminopentane Derivative, Intermediate and Process for Preparing Intermediate | FUJIMOTO CO., LTD. (JP) | 2009-05-14 | — | — | US | disclosed |
| US-20090124813-A1 | Process for Preparing Optically Active Aminopentane Derivative, Intermediate and Process for Preparing Intermediate | FUJIMOTO CO., LTD. (JP) | 2009-05-14 | — | — | US | disclosed |
| US-20090124813-A1 | Process for Preparing Optically Active Aminopentane Derivative, Intermediate and Process for Preparing Intermediate | FUJIMOTO CO., LTD. (JP) | 2009-05-14 | — | — | US | disclosed |
| EP-1905760-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE IN THE PROCESS AND PROCESS FOR PRODUCTION OF THE INTERMEDIATE | Fujimoto Co., Ltd. (JP) | 2008-04-02 | — | — | EP | disclosed |
| WO-2008000680-A1 | FLUOROUS TELOMERIC COMPOUNDS AND POLYMERS CONTAINING SAME | CLARIANT INTERNATIONAL LTD (CH) | 2008-01-03 | — | — | WO | disclosed |
| WO-2008000681-A1 | FLUOROUS TELOMERIC COMPOUNDS AND POLYMERS CONTAINING SAME | CLARIANT INTERNATIONAL LTD (CH) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124813-A1 | Process for Preparing Optically Active Aminopentane Derivative, Intermediate and Process for Preparing Intermediate | API5, CASP5, BAD | LMNA 618/4885CNR1 1907/4885ADRA1A 145/4885 |
| US-20100324300-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE AMINOPENTANE DERIVATIVE, INTERMEDIATE AND PROCESS FOR PREPARING INTERMEDIATE | API5, CASP5, BAD | LMNA 618/4885CNR1 1907/4885ADRA1A 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.