Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28308961 | 0.87 | TSHR (0.68) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL24847363 | 0.81 | TSHR (0.53) | ADRB2ADRB1ADRB3TSHRMEN1 | |
| SCHEMBL19631454 | 0.80 | TSHR (0.41) | TSHRL3MBTL1ALDH1A1ELANEHSD17B10 | |
| SCHEMBL30131119 | 0.80 | TSHR (0.41) | TSHRL3MBTL1ALDH1A1ELANEHSD17B10 | |
| SCHEMBL7879295 | 0.80 | TSHR (0.52) | ADRB2ADRB1ADRB3TSHRMEN1 | |
| SCHEMBL28735227 | 0.80 | NPC1 (0.49) | ADRB2ADRB1ADRB3TSHRMEN1 | |
| SCHEMBL7927977 | 0.80 | TSHR (0.55) | ADRB2ADRB1ADRB3TSHRMEN1 | |
| SCHEMBL18862636 | 0.78 | MAPK1 (0.55) | ADRB2ADRB1ADRB3TSHRKMT2A | |
| SCHEMBL24848615 | 0.77 | TSHR (0.53) | ADRB2ADRB1ADRB3TSHRMEN1 | |
| SCHEMBL1569293 | 0.77 | TSHR (0.80) | ADRB2ADRB1ADRB3TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274246-A1 | AMIDE COMPOUND AND USE THEREOF | 成都分迪药业有限公司 | 2023-01-05 | — | — | WO | disclosed |