Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2654989 | 0.83 | TSHR (0.47) | TSHRALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL24847363 | 0.81 | TSHR (0.53) | TSHRALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL1569293 | 0.81 | TSHR (0.80) | TSHRALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL29535471 | 0.81 | TSHR (0.80) | TSHRALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7879295 | 0.80 | TSHR (0.52) | TSHRALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL1629684 | 0.80 | ALDH1A1 (0.79) | TSHRALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7927977 | 0.80 | TSHR (0.55) | TSHRALDH1A1KMT2AMEN1L3MBTL1 | |
| O-Xylene SCHEMBL30462319 | 0.79 | CYP4F2 (0.54) | TSHRALDH1A1KMT2ACYP3A4LMNA | |
| SCHEMBL27501881 | 0.79 | TSHR (0.77) | TSHRALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7881875 | 0.78 | TSHR (0.50) | TSHRALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274246-A1 | AMIDE COMPOUND AND USE THEREOF | 成都分迪药业有限公司 | 2023-01-05 | — | — | WO | disclosed |