⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18771253 | 1.00 | — | — | |
| SCHEMBL21374218 | 0.75 | — | — | |
| SCHEMBL22105485 | 0.75 | — | — | |
| SCHEMBL16647393 | 0.72 | — | — | |
| SCHEMBL21789839 | 0.71 | — | — | |
| SCHEMBL9578180 | 0.71 | — | — | |
| SCHEMBL21789837 | 0.71 | — | — | |
| SCHEMBL25057685 | 0.71 | — | — | |
| SCHEMBL21799434 | 0.71 | — | — | |
| SCHEMBL19865677 | 0.71 | APLNR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002361-A1 | 2H-INDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | BIOGEN MA INC. | 2023-01-05 | — | — | US | disclosed |