Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.56 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.55 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 4/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | IL1B | P01584 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24847357 | 0.92 | CRBN (0.61) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL24847358 | 0.92 | CRBN (0.60) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL30820641 | 0.92 | CRBN (0.60) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL24848167 | 0.91 | CRBN (0.58) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL24848177 | 0.91 | CRBN (0.56) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL24847669 | 0.90 | CRBN (0.55) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL24847727 | 0.90 | CRBN (0.58) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL24847708 | 0.89 | CRBN (0.57) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL24848151 | 0.88 | CRBN (0.55) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL24847729 | 0.88 | CRBN (0.62) | CRBNDDB1GSPT1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274246-A1 | AMIDE COMPOUND AND USE THEREOF | 成都分迪药业有限公司 | 2023-01-05 | — | — | WO | disclosed |