SCHEMBL24848666

SCHEMBL24848666

c1ccc2nc(-n3c4ccccc4c4ccccc43)c(-c3cccc4oc5cc6c(cc5c34)oc3ccccc36)nc2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
AHR P35869 2/20 0.35
MEN1 O00255 4/20 0.33
MAPT P10636 4/20 0.33
KMT2A Q03164 4/20 0.33
KDM4E B2RXH2 4/20 0.32
HPGD P15428 4/20 0.32
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
ALDH1A1 P00352 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MITF O75030 1/20 0.31
SIRT2 Q8IXJ6 1/20 0.31
SIRT1 Q96EB6 1/20 0.31
HSD17B10 Q99714 2/20 0.30
GAA P10253 1/20 0.30
MAOA P21397 1/20 0.30
USP2 O75604 1/20 0.30
ESR1 P03372 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24036840 0.92 CYP1A2 (0.40) CYP1A2MEN1MAPTKMT2AKDM4E
SCHEMBL24849010 0.87 CYP1A2 (0.39) CYP1A2MEN1MAPTKMT2AKDM4E
SCHEMBL21213507 0.86 CYP1A2 (0.35) CYP1A2MEN1MAPTKMT2AKDM4E
SCHEMBL24848892 0.86 CYP1A2 (0.32) CYP1A2
SCHEMBL21281934 0.85 MAPT (0.33) AHRMEN1MAPTKMT2AKDM4E
SCHEMBL24848787 0.85 PRKDC (0.34) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL21716881 0.83 CYP1A2 (0.33) CYP1A2KDM4ENPC1RAB9A
SCHEMBL24848658 0.83 AHR (0.34) CYP1A2AHRMEN1MAPTKMT2A
SCHEMBL23026796 0.82 CYP1A2 (0.32) CYP1A2
SCHEMBL21716682 0.82 GSR (0.38) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277446-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-01-05 WO disclosed