SCHEMBL24848787

SCHEMBL24848787

c1ccc2nc(-n3c4ccccc4c4ccc5c6ccccc6sc5c43)c(-c3cccc4oc5cc6c(cc5c34)oc3ccccc36)nc2c1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.34
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PIK3CD O00329 1/20 0.30
PIK3CB P42338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24848900 0.89 PRKDC (0.31) PRKDCPIK3CDPIK3CB
SCHEMBL24848666 0.85 CYP1A2 (0.36) MEN1ALDH1A1POLBKMT2ASMN1; SMN2
SCHEMBL24848892 0.84 CYP1A2 (0.32)
SCHEMBL24802757 0.80 PRKDC (0.33) PRKDC
SCHEMBL24036840 0.77 CYP1A2 (0.40) MEN1ALDH1A1POLBKMT2A
SCHEMBL21281987 0.77 HSD17B10 (0.37) MEN1ALDH1A1POLBKMT2ASMN1; SMN2
SCHEMBL19655165 0.77 KDM4E (0.35) PRKDCSMN1; SMN2L3MBTL1PIK3CDPIK3CB
SCHEMBL26510224 0.77 PRKDC (0.34) PRKDCPIK3CDPIK3CB
SCHEMBL19473413 0.75 CYP1A2 (0.34)
SCHEMBL26530891 0.75 PRKDC (0.36) PRKDCPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277446-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-01-05 WO disclosed