Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL5143543 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2483151 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL2478477 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL5392228 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL5394406 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL6285485 | 0.82 | CYP19A1 (0.32) | — | |
| Fluoride Ion SCHEMBL5390710 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL6053839 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL8580551 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL5602376 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798306-B1 | Substituted indenyl unbridged metallocenes | PHILLIPS PETROLEUM CO (US) | 2002-05-22 | — | — | EP | claimed |
| US-5776851-A | COORDINATION POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 1998-07-07 | — | — | US | claimed |
| EP-0798306-A1 | Substituted indenyl unbridged metallocenes | PHILLIPS PETROLEUM COMPANY (US) | 1997-10-01 | — | — | EP | claimed |
| US-8389780-B2 | Polyalphaolefins and processes for forming polyalphaolefins | CHEMTURA CORPORATION (US) | 2013-03-05 | — | — | US | disclosed |
| EP-2395028-A1 | Process for removal of residual catalyst components | Chemtura Corporation (US) | 2011-12-14 | — | — | EP | disclosed |
| EP-2059538-B1 | PROCESS FOR REMOVAL OF RESIDUAL CATALYST COMPONENTS | CHEMTURA CORP (US) | 2011-10-19 | — | — | EP | disclosed |
| US-7601255-B2 | Process for removal of residual catalyst components | CHEMTURA CORPORATION (US) | 2009-10-13 | — | — | US | disclosed |
| EP-2059538-A2 | PROCESS FOR REMOVAL OF RESIDUAL CATALYST COMPONENTS | Chemtura Corporation (US) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008030387-A2 | PROCESS FOR REMOVAL OF RESIDUAL CATALYST COMPONENTS | CHEMTURA CORPORATION (US) | 2008-03-13 | — | — | WO | disclosed |
| US-20080053873-A1 | Process for removal of residual catalyst components | LANXESS SOLUTIONS US INC. | 2008-03-06 | — | — | US | disclosed |
| EP-1629018-A1 | CLASS OF METALLOCENES AND METHOD OF PRODUCING POLYETHYLENE | Univation Technologies LLC (US) | 2006-03-01 | — | — | EP | disclosed |
| CN-1093132-C | Metallocene compounds | BAYER AG (DE) | 2002-10-23 | — | — | CN | disclosed |
| WO-2001098406-A2 | POLYETHYLENE BLENDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2001-12-27 | — | — | WO | disclosed |
| US-20010034298-A1 | CATALYST FOR POLYMERIZATION OF ETHYLENE AND METHOD FOR PRODUCING ETHYLENE POLYMERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-10-25 | — | — | US | disclosed |
| CN-1229410-A | Metallocene compounds | BAYER AG (DE) | 1999-09-22 | — | — | CN | disclosed |
| CN-1229418-A | Process for preparing high-melting polyolefin | BAYER AG (DE) | 1999-09-22 | — | — | CN | disclosed |
| CN-1229416-A | Method for producing cycloolefin or (CO) polymers for industrial applications | BAYER AG (DE) | 1999-09-22 | — | — | CN | disclosed |
| CN-1228790-A | Method for producing thermoplastic elastomers | BAYER AG (DE) | 1999-09-15 | — | — | CN | disclosed |
| US-5776851-A | COORDINATION POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 1998-07-07 | — | — | US | disclosed |
| US-5693730-A | METALLOCENES HAVING MORE THAN ONE CENTRAL ATOM AND A SPECIAL BRIDGE STRUCTURE FOR PREPARING ISOTACTIC, HIGH-MOLECULAR-WEIGHT POLYMERS HAVING GOOD GRAIN MORPHOLOGY; PROPYLENE HOMO- AND COPOLYMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |