SCHEMBL24848701

SCHEMBL24848701

Clc1cccc2oc3ccc4c5ccccc5oc4c3c12

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AHR P35869 8/20 0.49
SMN1; SMN2 Q16637 3/20 0.44
TTR P02766 3/20 0.42
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 3/20 0.41
MAPT P10636 3/20 0.41
HPGD P15428 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ALOX5 P09917 2/20 0.40
MAOA P21397 2/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38
PGAM1 P18669 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31135769 1.00 AHR (0.49) AHRSMN1; SMN2TTRKDM4EALDH1A1
SCHEMBL23242811 0.87 MAPT (0.50) AHRSMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL18339171 0.86 AHR (0.56) AHRSMN1; SMN2TTRKDM4EALDH1A1
SCHEMBL24090333 0.86 AHR (0.54) AHRSMN1; SMN2TTRKDM4EALDH1A1
SCHEMBL22071327 0.85 AHR (0.47) AHRSMN1; SMN2ALDH1A1HPGDALOX5
SCHEMBL22737844 0.83 ALOX5 (0.51) AHRSMN1; SMN2TTRKDM4EALDH1A1
SCHEMBL31282478 0.83 AHR (0.43) AHRSMN1; SMN2TTRALDH1A1MEN1
SCHEMBL18348863 0.83 AHR (0.49) AHRSMN1; SMN2TTRKDM4EALDH1A1
SCHEMBL21019540 0.82 MAPT (0.46) AHRSMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL22698058 0.82 AHR (0.55) AHRSMN1; SMN2KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277446-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-01-05 WO disclosed