SCHEMBL24848797

SCHEMBL24848797

c1ccc2cc3c(cc2c1)c1ccccc1n3-c1nc2ccccc2nc1-c1ccc2c(c1)oc1cc3oc4ccccc4c3cc12

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHEK2 O96017 1/20 0.33
HCRTR1 O43613 1/20 0.33
MAOA P21397 1/20 0.32
CASP1 P29466 1/20 0.32
HSD17B10 Q99714 1/20 0.32
AHR P35869 2/20 0.32
MEN1 O00255 2/20 0.31
MAPT P10636 2/20 0.31
KMT2A Q03164 2/20 0.31
HPGD P15428 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
ATM Q13315 1/20 0.30
POLB P06746 1/20 0.30
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21213196 0.97 HCRTR1 (0.34) CHEK2HCRTR1CASP1HSD17B10AHR
SCHEMBL21716936 0.90 HCRTR1 (0.31) HCRTR1
SCHEMBL21716710 0.90 HCRTR1 (0.31) HCRTR1
SCHEMBL21716212 0.89 HCRTR1 (0.31) HCRTR1
SCHEMBL21716203 0.89 HCRTR1 (0.31) HCRTR1
SCHEMBL21213184 0.89 PIK3R1 (0.37) CHEK2HCRTR1CASP1HSD17B10NPC1
SCHEMBL21212946 0.89 PIK3R1 (0.37) CHEK2HCRTR1CASP1HSD17B10NPC1
SCHEMBL24275255 0.88 TDP1 (0.32) HCRTR1
SCHEMBL21213464 0.88 HCRTR1 (0.32) CHEK2HCRTR1AHR
SCHEMBL22277125 0.87 CASP1 (0.38) CHEK2CASP1HSD17B10AHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277446-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-01-05 WO disclosed