Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24833958 | 0.83 | KMT2A (0.63) | P2RY12GAAKDM4EALDH1A1GLA | |
| SCHEMBL7931748 | 0.82 | P2RY12 (0.82) | P2RY12GAAKDM4EALDH1A1GLA | |
| SCHEMBL7840881 | 0.82 | P2RY12 (0.61) | P2RY12GAAKDM4EALDH1A1GLA | |
| SCHEMBL24851241 | 0.80 | P2RY12 (0.62) | P2RY12GAAKDM4EALDH1A1GLA | |
| SCHEMBL92077 | 0.78 | GAA (0.82) | P2RY12GAAKDM4EALDH1A1GLA | |
| SCHEMBL22367061 | 0.78 | GAA (0.82) | P2RY12GAAKDM4EALDH1A1GLA | |
| SCHEMBL13412901 | 0.78 | GAA (0.82) | P2RY12GAAKDM4EALDH1A1GLA | |
| SCHEMBL29349876 | 0.78 | GAA (0.82) | P2RY12GAAKDM4EALDH1A1GLA | |
| Acridone SCHEMBL29641306 | 0.78 | ALDH1A1 (1.00) | GAAKDM4EALDH1A1GLAHTT | |
| Acridone SCHEMBL29360611 | 0.78 | ALDH1A1 (1.00) | GAAKDM4EALDH1A1GLAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146906-A1 | CASPASE-2 INHIBITOR COMPOUNDS | Kintsugi Therapeutics S.L. (ES) | 2024-07-11 | — | — | WO | disclosed |
| WO-2023275357-A1 | CASPASE-2 INHIBITOR COMPOUNDS | Kintsugi Therapeutics S.L. (ES) | 2023-01-05 | — | — | WO | disclosed |