Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24850469 | 0.90 | GAA (0.45) | GAAKMT2AKDM4EMAPK8SMN1; SMN2 | |
| SCHEMBL316348 | 0.90 | SMN1; SMN2 (0.48) | GAAKMT2AKDM4EMAPK8SMN1; SMN2 | |
| SCHEMBL5697678 | 0.86 | MAPT (0.45) | GAAKMT2AKDM4EMAPK8SMN1; SMN2 | |
| SCHEMBL18329658 | 0.86 | SMN1; SMN2 (0.44) | GAAKMT2AKDM4EMAPK8SMN1; SMN2 | |
| SCHEMBL12846025 | 0.86 | GAA (0.43) | GAAKMT2AKDM4EMAPK8SMN1; SMN2 | |
| SCHEMBL23793834 | 0.86 | GNAI3 (0.44) | GAAKMT2AKDM4EMAPK8SMN1; SMN2 | |
| SCHEMBL21236012 | 0.84 | GNAI3 (0.50) | GAAKMT2AKDM4EMAPK8SMN1; SMN2 | |
| SCHEMBL4407502 | 0.84 | SMN1; SMN2 (0.43) | GAAKMT2AKDM4EMAPK8SMN1; SMN2 | |
| SCHEMBL2302254 | 0.83 | GAA (0.50) | GAAKMT2AKDM4EMAPK8EPHX2 | |
| SCHEMBL23793654 | 0.83 | GNAI3 (0.52) | KMT2AEPHX2GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230006250-A1 | IONIC CYCLIC NITROXYL RADICAL OLIGOMERS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2023-01-05 | — | — | US | disclosed |