Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.43 |
| ▸ | FOS | P01100 | 6/20 | 0.43 |
| ▸ | JUN | P05412 | 6/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.43 |
| ▸ | RELA | Q04206 | 6/20 | 0.43 |
| ▸ | ATF1 | P18846 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23625406 | 0.87 | SYK (0.50) | SYKNFKB1FOSJUNNFKB2 | |
| SCHEMBL23620399 | 0.81 | SYK (0.54) | SYKNFKB1FOSJUNNFKB2 | |
| SCHEMBL14810384 | 0.81 | KDM4E (0.57) | SYKNFKB1FOSJUNNFKB2 | |
| SCHEMBL2523948 | 0.80 | SYK (0.53) | SYKNFKB1FOSJUNNFKB2 | |
| SCHEMBL22866255 | 0.78 | ALDH1A1 (0.55) | SYKNFKB1FOSJUNNFKB2 | |
| SCHEMBL17764556 | 0.78 | SYK (0.51) | SYKNFKB1FOSJUNNFKB2 | |
| SCHEMBL18341477 | 0.78 | IRAK4 (0.41) | KDM4EALDH1A1MAPTNPC1MEN1 | |
| SCHEMBL29076116 | 0.77 | ALDH1A1 (0.49) | SYKNFKB1FOSJUNNFKB2 | |
| SCHEMBL10050288 | 0.76 | NR2F2 (0.56) | SYKNFKB1FOSJUNNFKB2 | |
| SCHEMBL18168237 | 0.76 | PDE4B (0.50) | SYKNFKB1FOSJUNNFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278483-A1 | COMPOUNDS HAVING 1H-PYRAZOLO[4,3-C]PYRIDIN-6-AMINOS AS THERAPEUTIC AGENTS | LOMOND THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2023278483-A1 | COMPOUNDS HAVING 1H-PYRAZOLO[4,3-C]PYRIDIN-6-AMINOS AS THERAPEUTIC AGENTS | LOMOND THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |