Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL2485228

B.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.91

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FDPS P14324 1/20 0.91
▸ BLM P54132 1/20 0.91
▸ TDP1 Q9NUW8 1/20 0.91
▸ CA4 P22748 1/20 0.37
▸ CA2 P00918 1/20 0.36
▸ INPPL1 O15357 2/20 0.35
▸ INPP5A Q14642 2/20 0.35
▸ SMPD1 P17405 1/20 0.35
▸ INPP5B P32019 1/20 0.35
▸ BTN3A1 O00481 2/20 0.35
▸ ITPR3 Q14573 3/20 0.33
▸ SLC34A1 Q06495 1/20 0.33
▸ ITPR2 Q14571 1/20 0.33
▸ ITPR1 Q14643 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL292348 0.95 FDPS (1.00) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL29634664 0.95 — —
Pyrophosphoric Acid SCHEMBL8851914 0.95 FDPS (1.00) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL3654 0.95 — —
Pyrophosphoric Acid SCHEMBL23537746 0.91 FDPS (0.91) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL396637 0.91 FDPS (0.91) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL714818 0.91 FDPS (0.91) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL21433694 0.91 FDPS (0.91) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL21145230 0.91 FDPS (0.91) FDPSBLMTDP1CA4CA2
Pyrophosphoric Acid SCHEMBL11171410 0.91 FDPS (0.91) FDPSBLMTDP1CA4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9067964-B2 Complex and method for enhancing nuclear delivery OLIGOMER SCIENCES AB (SE) 2015-06-30 — — US disclosed
US-20110306138-A1 COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY OLIGOMER SCIENCES AB (SE) 2011-12-15 — — US disclosed
EP-2376518-A1 A COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY Avaris AB (SE) 2011-10-19 — — EP disclosed
WO-2010071587-A1 A COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY AVARIS AB (SE) 2010-06-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110306138-A1 COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY SNRPE, SNRPA, HNRNPH3 FDPS 4137/4885BLM 3298/4885TDP1 864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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