Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | DDO | Q99489 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24851821 | 0.85 | KDM4E (0.55) | IL4I1KDM4EHSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL31192201 | 0.85 | KDM4E (0.55) | IL4I1KDM4EHSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL24851784 | 0.80 | IL4I1 (0.60) | IL4I1KDM4EHSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL24852024 | 0.79 | IL4I1 (0.59) | IL4I1KDM4EHSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL24852992 | 0.79 | IL4I1 (0.53) | IL4I1KDM4EHSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL24852147 | 0.78 | IL4I1 (0.56) | IL4I1KDM4EHSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL24852993 | 0.78 | KDM4E (0.53) | IL4I1KDM4EHSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL24851822 | 0.77 | IL4I1 (0.56) | IL4I1KDM4EHSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL24851708 | 0.77 | IL4I1 (0.63) | IL4I1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL32681268 | 0.77 | KDM4E (0.67) | IL4I1KDM4EHSD17B10ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278222-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2023-01-05 | — | — | WO | disclosed |