SCHEMBL2485320

SCHEMBL2485320

Cc1cccc(CC2CCCC(=O)O2)c1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.38
SLC6A4 P31645 5/20 0.36
SLC6A2 P23975 4/20 0.36
SLC6A3 Q01959 3/20 0.36
CYP2D6 P10635 2/20 0.36
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
POLB P06746 1/20 0.33
TBXA2R P21731 1/20 0.33
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
NR3C2 P08235 1/20 0.33
CYP1A2 P05177 2/20 0.33
HPGD P15428 2/20 0.32
CTSV O60911 2/20 0.32
CTSL P07711 2/20 0.32
CTSB P07858 2/20 0.32
CTSS P25774 2/20 0.32
CTSK P43235 2/20 0.32
CTSC P53634 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2700550 0.91 CYP1A2 (0.41) P2RX7SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL577122 0.78 ALDH1A1 (0.47) SLC6A4SLC6A2CYP2D6HPGD
SCHEMBL7634585 0.73 GRM2 (0.46) SLC6A4SLC6A2SLC6A3CYP2D6POLB
SCHEMBL14248992 0.72 ALDH1A1 (0.42) P2RX7SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL5688628 0.69 GRM2 (0.45) SLC6A4SLC6A2SLC6A3POLB
SCHEMBL576948 0.69 ALDH1A1 (0.49) P2RX7SLC6A4SLC6A2CYP2D6HPGD
SCHEMBL9233923 0.69 PARP1 (0.45)
SCHEMBL16449013 0.68
SCHEMBL919276 0.68
SCHEMBL11860254 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2378602-A2 Nonaqueous electrolyte for recherable battery, and recharchable battery with nonaqueous electrolyte Mitsubishi Chemical Corporation (JP) 2011-10-19 EP disclosed