SCHEMBL24853232

SCHEMBL24853232

c1ccc(-c2cc(-c3nc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5ccccc54)n3)cc3oc4ccccc4c23)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.33
TSHR P16473 4/20 0.32
KDM4E B2RXH2 4/20 0.32
ALDH1A1 P00352 4/20 0.32
MAPK1 P28482 2/20 0.32
LMNA P02545 2/20 0.32
POLB P06746 2/20 0.32
HSD17B10 Q99714 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CDC14B O60729 1/20 0.32
CDC14A Q9UNH5 1/20 0.32
ALOX15 P16050 1/20 0.32
RAB9A P51151 2/20 0.31
HPGD P15428 2/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
NPC1 O15118 1/20 0.31
CA12 O43570 1/20 0.31
TNKS O95271 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23862749 0.96 MAPT (0.34) MAPTTSHRKDM4EALDH1A1MAPK1
SCHEMBL24701702 0.94 MAPT (0.31) MAPTTSHRKDM4EALDH1A1MAPK1
SCHEMBL21583495 0.94 MAPT (0.33) MAPTTSHRKDM4EALDH1A1MAPK1
SCHEMBL21583507 0.93 PLA2G2A (0.33) MAPTTSHRKDM4EALDH1A1MAPK1
SCHEMBL24853233 0.91 KDM4E (0.35) KDM4ELMNATP53SMN1; SMN2ATM
SCHEMBL24701093 0.91 MAPT (0.33) MAPTTSHRKDM4EALDH1A1MAPK1
SCHEMBL23862805 0.90 PLA2G2A (0.33) MAPTTSHRKDM4EALDH1A1MAPK1
SCHEMBL26282767 0.90
SCHEMBL23862787 0.90 MAPT (0.31) MAPTTSHRKDM4EALDH1A1MAPK1
SCHEMBL25965212 0.89 KDM4E (0.37) MAPTTSHRKDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023273357-A1 CARBAZOLE-CONTAINING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE 南京高光半导体材料有限公司 2023-01-05 WO disclosed